Advanced Diagnostic Procedures for Male Fertility
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Hormone Analysis: Blood tests measure levels of hormones like testosterone, LH (luteinizing hormone), FSH (follicle-stimulating hormone), and prolactin to assess sperm production and overall endocrine health.
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Genetic Testing:
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Karyotyping: Identifies chromosomal abnormalities that may affect sperm production or fertility.
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Y Chromosome Microdeletion Testing: Detects specific deletions on the Y chromosome that can lead to low or absent sperm production.
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CFTR Gene Mutation Testing: Determines if mutations in the cystic fibrosis gene are causing absence of the vas deferens, impacting sperm delivery.
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Semen Analysis and Advanced Sperm Function Tests:
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Sperm DNA Fragmentation: Analyzes DNA integrity in sperm; high levels of fragmentation are linked to reduced fertility and miscarriage.
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Sperm Chromatin Structure Assay (SCSA): Measures the DNA integrity and chromatin structure in sperm.
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Reactive Oxygen Species (ROS) Testing: Measures oxidative stress levels, which can impact sperm quality.
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Anti-Sperm Antibody Test: Checks for antibodies that may attack sperm, affecting motility and fertilization potential.
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Testicular Biopsy: Used in cases of azoospermia to examine the presence and development of sperm in the testes, helping to differentiate between obstructive and non-obstructive causes of infertility.
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Scrotal and Transrectal Ultrasound: Provides detailed imaging of the reproductive organs, detecting blockages, varicoceles, or structural abnormalities that can impact fertility.
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Sperm Aneuploidy Test: Detects chromosomal abnormalities in sperm, which may affect fertility, miscarriage rates, or developmental issues in offspring.
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Vasography: An imaging test to detect obstructions in the vas deferens, useful for men with obstructive azoospermia.
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Most of the tests are done within the Easymom facility. Some tests may be outsourced based on the availability.